Manhattan style is one popular way to build ham radio electronics. It involves small "pads", typically circular dots roughly 3 mm diameter punched out of plain copper-clad board.
The pads are super-glued onto the "substrate", a large copper-clad board. Each component is mounted right-side-up by soldering its pins to pads.
The builders try to make each pad represent one node in the schematic -- every pin that connects to that node is soldered to one pad, when possible. When it's not possible, hook-up wire is used to connect pad-to-pad and pad-to-DIP-socket-pin.
Each ground pin of a component is soldered directly to the substrate.
K7QO has an excellent description of the technique: http://www.k7qo.net/manart.pdf
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